Pathophysiology Week 1 Case 3
Seizure
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Epilepsy
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SIADH
CORRECT CLINICAL REASONING: Imipramine can cause SIADH. Normally in the Hypothalamus there are osmoreceptors that Respond to hyperosmolality by signaling the posterior pituitary gland to secrete Anti-Diuretic Hormone- which will tell the kidneys to retain free water to keep sodium levels in check. IT will also stimulate thirst. This usually occurs when sodium goes over 142 and stops when it goes below 134. In SIADH – sudden 1nappropriate Anti-diuretic Hormone syndrome the kidneys just start retaining all the free water for no reason. This drives the sodium down as evidenced by the low sodium of our patient at 126. Hyponatremia causes a fluid shift from ECF-ICF causing cells to swell which can cause a seizure.
Male 27 years old CHIEF COMPLAINT: Seizure
After reviewing the case, what is the most likely pathophysiology →
MEDICAL CHART
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